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Article

c-jun and Egr-1 Participate in DNA Synthesis and Cell Survival in Response to Ionizing Radiation Exposure

1 Dec 1995

Abstract excerpt

Exposure of mammalian cells to ionizing radiation results in the induction of the immediate early genes, c-jun and Egr-1, which encode transcription factors implicated in cell growth as well as the cellular response to oxidative stress. We studied the role of these immediate early genes in cell cycle kinetics and cell survival following x-irradiation of clones containing inducible dominant negatives to c-jun and...

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PMID: 8530452
DOI: 10.1074/jbc.270.51.30303

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Source receipt: pubmed, retrieved 7 Sept 2026.

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