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Article

The ability of Fos family members to produce phenotypic changes in epithelioid cells is not directly linked to their transactivation potentials.

Oncogene - 18 Jul 2002

Andersen Henriette, Mahmood Shaukat, Tkach Vadim, Cohn Martin, Kustikova Olga, Grigorian Mariam, Berezin Vladimir, Bock Elisabeth, Lukanidin Eugene, Tulchinsky Eugene

Abstract excerpt

Numerous studies have revealed distinct functions of Fos proteins in different mouse tissues and cell lines. Here, we perform a direct comparison of the features of exogenous c-Fos, Fra-1 and Fra-2 proteins expressed in murine tumor cells of epithelial origin, CSML0. Although transactivation potential of c-Fos is much stronger than that of Fra-1 and Fra-2, all three proteins are capable of modulating...

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Identifiers

PMID: 12101423
DOI: 10.1038/sj.onc.1205590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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