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Article

C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma

1 Oct 2008

Abstract excerpt

Members of the Fos protein family dimerise with Jun proteins to form the AP-1 transcription factor complex. They have a central function in proliferation and differentiation of normal tissue as well as in oncogenic transformation and tumour progression. We analysed the expression of c-Fos, FosB, Fra-1 and Fra-2 to investigate the function of Fos transcription factors in ovarian cancer. A total of 101 patients...

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PMID: 18854825
DOI: 10.1038/sj.bjc.6604650

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