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Article

Degradation of cellular and viral Fos proteins.

Biochimie - 1 Jan 2000

Acquaviva C, Ferrara P, Bossis G, Brockly F, Salvat C, Jariel-Encontre I, Piechaczyk M

Abstract excerpt

c-Fos proto-oncoprotein is a short-lived transcription factor with oncogenic potential. We have shown that it is massively degraded by the proteasome in vivo under various experimental conditions. Other proteolytic systems including lysosomes and calpains, might, however, also marginally operate on it. Although there is evidence that c-Fos can be ubiquitinylated in vitro, the unambiguous demonstration that...

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Identifiers

PMID: 11295497
DOI: 10.1016/s0300-9084(01)01243-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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