Article
Genetic control of the CD4/CD8 T-cell ratio in humans.
Nature medicine - 1 Dec 1995
Amadori A, Zamarchi R, De Silvestro G, Forza G, Cavatton G, Danieli G A, Clementi M, Chieco-Bianchi L
Abstract excerpt
We studied the genetic pattern of inheritance of the ratio between circulating CD4+ and CD8+ T lymphocytes in a population of healthy donors. The distribution of the CD4/CD8 ratio in males and females was significantly different and was significantly affected by age. In 46 randomly selected famil...
Topics
- Adult
- Age Factors
- CD4-CD8 Ratio
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Female
- Genes, Recessive
- Genetics, Population
- Humans
- Italy
- Male
- Models, Genetic
- Phenotype