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Article

An investigation of transmission ratio distortion in the central region of the human MHC.

Genes and immunity - 1 Jan 2006

Hanchard N, Rockett K, Udalova I, Wilson J, Keating B, Koch O, Nijnik A, Diakite M, Herbert M, Kwiatkowski D

Abstract excerpt

Transmission ratio distortion (TRD) describes a significant departure from expected Mendelian inheritance ratios that is fundamental to both the biology of reproduction and statistical genetics. The relatively high fetal wastage in humans, with consequent selection of alleles in utero, makes it likely that TRD is prevalent in the human genome. The central region of the human major histocompatibility complex (MHC)...

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Source

Identifiers

PMID: 16341054
DOI: 10.1038/sj.gene.6364277

Genes

TRD
CLIC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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