Article
The progesterone receptor can regulate transcription in the absence of a functional TATA box element.
The Journal of biological chemistry - 5 Oct 1990
Thomson A A, Ham J, Bakker O, Parker M G
Abstract excerpt
We have investigated the importance of the TATA box element in the induction of transcription by the progesterone receptor. Transcription was analyzed from promoters containing a steroid response element upstream of a wild-type or mutated TATA box. Mutation of the TATA box resulted in a loss of c...
Topics
- Animals
- Base Sequence
- Cell Line
- Cloning, Molecular
- Gene Expression Regulation
- Molecular Sequence Data
- Mutation
- Promegestone
- Promoter Regions, Genetic
- Receptors, Progesterone
- Restriction Mapping
- TATA Box
- Thymidine Kinase
- Transcription, Genetic
- Transfection
