Article
The chaperone-like protein YerA of Yersinia pseudotuberculosis stabilizes YopE in the cytoplasm but is dispensible for targeting to the secretion loci.
Molecular microbiology - 1 May 1995
Frithz-Lindsten E, Rosqvist R, Johansson L, Forsberg A
Abstract excerpt
The virulence plasmid-encoded YopE cytotoxin of Yersinia pseudotuberculosis is secreted across the bacterial membranes and subsequently translocated into the eukaryotic cell. Translocation of YopE into target cells was recently shown to be polarized and only occurred at the zone of contact between the pathogen and the eukaryotic cell. Immunogold electron microscopy on cryosectioned Y. pseudotuberculosis revealed...
Topics
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Base Sequence
- Biological Transport, Active
- Cytoplasm
- DNA, Bacterial
- Genes, Bacterial
- HeLa Cells
- Humans
- Microscopy, Immunoelectron