The cytotoxic protein YopE of Yersinia obstructs the primary host defence.

doi:10.1111/j.1365-2958.1990.tb00635.x

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Article

The cytotoxic protein YopE of Yersinia obstructs the primary host defence.

Molecular microbiology - 1 Apr 1990

Rosqvist R, Forsberg A, Rimpiläinen M, Bergman T, Wolf-Watz H

Abstract excerpt

It has previously been shown that the plasmid-encoded YopE protein of Yersinia pseudotuberculosis is a virulence determinant. In this study, HeLa cells, macrophages and mice were used as different model systems to determine the actual role of YopE in the virulence process. The YopE protein mediat...

Topics

Animals
Bacterial Outer Membrane Proteins
Bacterial Proteins
Biological Transport
Cytotoxins
Genes, Bacterial
HeLa Cells
Humans
Mice
Mutation
Trans-Activators
Virulence
Virus Cultivation
Yersinia pseudotuberculosis
Yersinia pseudotuberculosis Infections

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