Article
YopK of Yersinia pseudotuberculosis controls translocation of Yop effectors across the eukaryotic cell membrane.
Molecular microbiology - 1 Apr 1997
Holmström A, Petterson J, Rosqvist R, Håkansson S, Tafazoli F, Fällman M, Magnusson K E, Wolf-Watz H, Forsberg A
Abstract excerpt
Introduction of anti-host factors into eukaryotic cells by extracellular bacteria is a strategy evolved by several Gram-negative pathogens. In these pathogens, the transport of virulence proteins across the bacterial membranes is governed by closely related type III secretion systems. For pathogenic Yersinia, the protein transport across the eukaryotic cell membrane occurs by a polarized mechanism requiring two...
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