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Article

[Application of molecular diagnosis to human lung cancer].

Rinsho byori. The Japanese journal of clinical pathology - 1 Aug 1995

Isobe T

Abstract excerpt

Recent developments in the molecular genetics of human cancers shows the importance of multiple genetic alterations in the pathogenesis of these lesions. DNA diagnostic techniques are being introduced rapidly into the clinical laboratory setting. 1) In lung cancer, several oncogenes and tumor suppressor genes, such as ras, myc, p53, RB, allelic loss of chromosomes, play very important roles. These genetic changes...

Topics

DNA Topoisomerases, Type I
Drug Resistance
Genes, Tumor Suppressor
Genetic Predisposition to Disease
Humans
Lung Neoplasms
Mutation
Oncogenes

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7474438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7474438-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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