Article
[Molecular approach to lung cancer].
Nihon Kyobu Shikkan Gakkai zasshi - 1 Dec 1995
Takahashi T, Ueda R, Takahashi T
Abstract excerpt
Lung cancer is associated with a number of cytogenetic abnormalities, such as chromosomal deletions on 3p, 12q, and 17p, which suggest the involvement of multiple tumor suppressor genes. These findings led to the discovery of the inactivation of the Rb and p53 genes in lung cancer. Recent remarkable progress in molecular biology should add a number of genes to the list of tumor suppressor gene involved in the...
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