Article
[The relationship between the high inducibility genotype of CYP450IA1 and lung cancer susceptibility].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 Feb 1996
Pi J, Sun G, Lü X
Abstract excerpt
OBJECTIVE: To evaluate the role of polymorphism of CYP450IA1 gene in the susceptibility of lung cancer. METHODS: The polymorphism of CYP450IA1 gene in 149 lung cancer patients and 208 healthy controls were investigated by PCR technique. RESULTS: The high inducibility genotype (Val/Val type) of CYP450IA1 in lung cancer patients was 16.1%, which was significantly higher than that of controls, 8.7%. According to...
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