[Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to lung cancer--relevance to smoking].

Article

[Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to lung cancer--relevance to smoking].

Nihon rinsho. Japanese journal of clinical medicine - 1 Feb 1996

Uematsu F

Abstract excerpt

Lung cancer has been associated with smoking and many carcinogenic compounds are thought to contribute to the origin of lung cancer. Most of these carcinogens exert their carcinogenicity after conversion to more potent forms through reactions mediated by drug-metabolizing enzymes, such as cytochr...

Topics

Enzymes
Genetic Predisposition to Disease
Humans
Lung Neoplasms
Pharmaceutical Preparations
Polymorphism, Genetic
Smoking

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