Article
[Genetic investigations for lung carcinoma].
Nihon Geka Gakkai zasshi - 1 Jun 2002
Shirakusa Takayuki, Noda Naotaka, Matsuzoe Daisuke
Abstract excerpt
Lung carcinoma is a common malignant disease in adults. Various genetic changes associated with small cell and non-small cell lung carcinoma are now known. There are two types of genetic change which influence tumor growth and patient prognosis. Among oncogenes, c-myc, K-ras, and erbB-2 are considered to play important roles in lung carcinogenesis. The p53 suppressor gene is highly expressed in small and...
Topics
- Diagnosis, Differential
- Genes, erbB-2
- Genes, p53
- Genes, ras
- Humans
- Lung Neoplasms
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational