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Article

Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression.

Journal of virology - 1 Nov 1995

Michael N L, Chang G, d'Arcy L A, Tseng C J, Birx D L, Sheppard H W

Abstract excerpt

We have studied the sequence and function of the human immunodeficiency virus type 1 (HIV-1) nef genes from nine patients with highly divergent rates of disease progression enrolled in a longitudinal study of HIV disease. Over an average of 7.8 years of follow-up, three patients had net positive changes in CD4+ T-cell counts, three patients had net negative changes in CD4+ T cells but did not develop AIDS, and...

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Identifiers

PMID: 7474087
DOI: 10.1128/JVI.69.11.6758-6769.1995
PMCID: PMC189587

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression.PMID 7474087Read ↗

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