Article
Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression.
Journal of virology - 1 Nov 1995
Michael N L, Chang G, d'Arcy L A, Tseng C J, Birx D L, Sheppard H W
Abstract excerpt
We have studied the sequence and function of the human immunodeficiency virus type 1 (HIV-1) nef genes from nine patients with highly divergent rates of disease progression enrolled in a longitudinal study of HIV disease. Over an average of 7.8 years of follow-up, three patients had net positive...
Topics
- Acquired Immunodeficiency Syndrome
- Adult
- Amino Acid Sequence
- Base Sequence
- CD4 Lymphocyte Count
- DNA Primers
- Disease Progression
- Follow-Up Studies
- Genes, nef
- Genetic Variation
- HIV Infections
- HIV Seropositivity
- HIV-1
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Phylogeny