Article
Nef and LTR sequence variation from sequentially derived human immunodeficiency virus type 1 isolates.
Virology - 1 Apr 1995
McNearney T, Hornickova Z, Templeton A, Birdwell A, Arens M, Markham R, Saah A, Ratner L
Abstract excerpt
Variation in HIV-1 nef and LTR DNA sequences was assessed longitudinally during disease progression in four HIV-1-infected subjects. Point mutations were found among quasispecies obtained at a single time point in each individual, with increasing diversity with disease progression in two of three patients for whom sufficient data were available for analysis. Deletions and rearrangements were more common in late...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
