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Article

Differing activation pathways for 2-acetylaminofluorene to a mutagen in vitro.

Mutation research - 1 Jan 2000

McGregor D B, McConville M, Menzies C, Prentice R D

Abstract excerpt

The mutagenicity of 2-acetylaminofluorene (AAF) in S. typhimurium TA 1538 was investigated using Ames' test and activation systems based upon rat- or cotton rat-liver post-mitochondrial supernatant (S9) fractions. Part of this study involved sub-fractionation of S9 into microsomes (M) and 100,000 X g supernatant (S100) fractions. With a rat liver-derived fractions, mos activity was associated with S100;...

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Identifiers

PMID: 6750372
DOI: 10.1016/0165-1218(82)90144-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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