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Article

Evidence for site-specific bioactivation of alachlor in the olfactory mucosa of the Long-Evans rat.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Jun 1999

Wetmore B A, Mitchell A D, Meyer S A, Genter M B

Abstract excerpt

Alachlor (2-chloro-2',6'-diethyl-N-[methoxymethyl]-acetanilide) is a restricted-use chloracetanilide herbicide which has been shown previously to produce a dose-dependent incidence of olfactory mucosal tumors in rats following chronic dietary exposure. However, the mechanism of alachlor carcinogenicity is poorly understood. Alachlor was administered i.p. to male Long-Evans rats for up to 28 days at doses that are...

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PMID: 10416265
DOI: 10.1093/toxsci/49.2.202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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