Androgen receptor-mediated genetic differences in 2-acetylaminofluorene and dimethylnitrosamine mutagenesis in vitro.

Article

Androgen receptor-mediated genetic differences in 2-acetylaminofluorene and dimethylnitrosamine mutagenesis in vitro.

Anticancer research - 1 Jan 2000

Fysh J M, Andrews L S, Nebert D W

Abstract excerpt

When 2-acetylaminofluorene and dimethylnitrosamine mutagenesis rates in the Salmonella/liver in vitro system were studied with C3H/HeJ mouse kidney or liver postmitochondrial supernatant (S-9) fractions, sex differences (male much greater than female) of 10- to 30-fold were found in kidney but no...

Topics

2-Acetylaminofluorene
Animals
DNA
Dihydrotestosterone
Dimethylnitrosamine
Glucuronidase
In Vitro Techniques
Kidney
Liver
Mice
Mice, Inbred Strains
Mutation
Receptors, Androgen
Receptors, Steroid
Sex Factors

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