Relationship of Syrian inbred hamster acetylator genotype to the mutagenic activation of 2-aminofluorene.

doi:10.1093/mutage/5.3.233

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Article

Relationship of Syrian inbred hamster acetylator genotype to the mutagenic activation of 2-aminofluorene.

Mutagenesis - 1 May 1990

Yerokun T, Hein D W, Ferguson R J, Ogolla F, Heflich R H, Minor T Y, Trinidad A, Kirlin W G, Andrews A F

Abstract excerpt

The genetic constitution of mammalian enzymes involved in the metabolism of xenobiotics is one of the important factors responsible for large inter-individual differences in the rate of biotransformation and consequently the magnitude of genotoxic effects exerted in target tissues. The present st...

Topics

Acetyl Coenzyme A
Acetylation
Animals
Biotransformation
Carcinogens
Cricetinae
Fluorenes
Genotype
In Vitro Techniques
Male
Mesocricetus
Mutagenicity Tests
Mutagens
Polymorphism, Genetic
Submitochondrial Particles

Source

Open in PubMed

Identifiers

PMID: 2385177
DOI: 10.1093/mutage/5.3.233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2385177-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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