Article
The biochemical mechanisms of the plant activation of promutagenic aromatic amines.
Environmental and molecular mutagenesis - 1 Jan 1990
Wagner E D, Verdier M M, Plewa M J
Abstract excerpt
Using specific monooxygenase and oxidase inhibitors in a plant cell/microbe coincubation assay, the biochemical mechanisms of the plant activation of two aromatic amines were compared. The biological endpoints included mutation induction, inhibition of mutagenicity, viability of the plant cells (activating system), and viability of the microbial cells (genetic indicator organism). The activation of...
Topics
- Acetaminophen
- Benzoflavones
- Biotransformation
- Catechin
- Cell Line
- Ditiocarb
- Fluorenes
- Methimazole
- Metyrapone
- Mutagens
- Mutation
- Oxidoreductases