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Article

Mutagenicity studies of p-substituted benzyl derivatives in the Ames Salmonella plate-incorporation assay.

Mutation research - 1 Jan 2000

Ball J C, Foxall-VanAken S, Jensen T E

Abstract excerpt

The mutagenicity of 24 benzyl derivatives, containing a variety of substituents and leaving groups, were assayed in strain TA100 using the Ames plate-incorporation assay. p-Nitrobenzyl chloride (12 000 revertants/mumole), p-nitrobenzyl tosylate (6100 revertants/mumole), and p-acetoxybenzyl chloride (100 revertants/mumole) were mutagenic; none of the remaining 21 compounds were mutagenic. p-Nitrobenzyl chloride...

Topics

Benzyl Compounds
Gas Chromatography-Mass Spectrometry
Hydrolysis
Mutagenicity Tests
Mutagens
Mutation
Salmonella typhimurium
Structure-Activity Relationship

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 6392873
DOI: 10.1016/0165-1218(84)90037-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6392873-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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