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Article

Mutagenicity of polycyclic aromatic compounds (PAC) identified in source emissions and ambient air.

Mutation research - 1 Jan 2000

Møller M, Hagen I, Ramdahl T

Abstract excerpt

Several polycyclic aromatic compounds (PAC) including nitrated and oxygenated derivatives of polycyclic aromatic hydrocarbons (PAH) were tested for mutagenic activity in the Salmonella/microsome assay. Among the compounds tested the isomer mix of nitro-1-hydroxypyrenes showed the highest direct mutagenic response in both the Salmonella strain TA98 and TA100 (1251 revertants/micrograms and 463...

Topics

Air Pollutants
Animals
Biotransformation
Dose-Response Relationship, Drug
Male
Microsomes, Liver
Mutation
Polycyclic Compounds
Rats
Salmonella typhimurium
Structure-Activity Relationship

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 3894960
DOI: 10.1016/0165-1218(85)90110-7

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3894960-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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