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Article

[Mechanism of functioning of aminoacyl-tRNA-synthetases].

Molekuliarnaia biologiia - 1 Jan 2000

Malygin E G, Kiselev L L

Abstract excerpt

The article reviews the data available concerning the kinetics of reactions catalysed by eukaryotic and procaryotic aminoacyl-tRNA synthetases (E.C.6.1.1). It is shown that most of these enzymes operate in accordance with the flip-flop mechanism although individual variations do exist. It is stressed that a simplified kinetic approach of Cleland is inappropriate if applied to the aminoacyl-tRNA synthetases where...

Topics

Amino Acyl-tRNA Synthetases
Kinetics
Models, Biological
Mutation
Protein Biosynthesis
RNA, Transfer
RNA, Transfer, Amino Acyl
Substrate Specificity

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 6390174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6390174-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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