Article
A dynamical model of programmed -1 ribosomal frameshifting.
Journal of theoretical biology - 7 Nov 2013
Xie Ping
Abstract excerpt
Programmed -1 ribosomal frameshifting is the most widely used translational recoding mechanism of RNA viruses. How the frameshifting occurs at the slippery sequence on the presence of a downstream mRNA pseudoknot has not been fully understood. Here, we present systematical analysis of the -1 frameshifting that can occur during every transition step in elongation phase of protein synthesis by Escherichia coli...
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