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Article

Activation of mutagens in cooked ground beef by human-liver microsomes.

Mutation research - 1 Jan 2000

Felton J S, Healy S K

Abstract excerpt

The total organic base fraction purified from fried ground beef is metabolized by human-liver microsomes to form mutagens detectable by the Ames/Salmonella bacterial assay. The mutagens produced have an absolute requirement for metabolic activation; without it, no increase in the number of revertants over background is seen. Microsomes from human liver activate the mutagens significantly more than microsomes from...

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PMID: 6379442
DOI: 10.1016/0165-7992(84)90043-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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