Article

Differential Genotoxicity of Polygoni Multiflori in Rat and Human: Insights from Ames Test and S9 Metabolic Activation System

2024-05-02

Abstract excerpt

<title>Abstract</title> The Ames test is used worldwide to initially screen the mutagenic potential of new chemicals. In the standard Ames test, <italic>S. typhimurium</italic>strains (TA100, TA98, TA1535, and TA1537) and <italic>Escherichia coli</italic> (WP2uvrA) are treated with substances with/without cytochrome P450s (CYPs)-induced rat S9 fractions for identifying mutagens and pro mutagens. However, many...

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Literature Corpus work: c299efd9-ceed-5760-9bb6-873120a9a259
DOI: 10.21203/rs.3.rs-4204575/v1

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