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Systematic analysis of gut bacterial carcinogen metabolism and its functional consequences

2024-05-21

Abstract excerpt

<h4>Summary</h4> Organic carcinogens, in particular DNA-reactive compounds, contribute to the irreversible initiation step of tumorigenesis through introduction of genomic instability. Although carcinogen bioactivation and detoxification by human enzymes has been extensively studied, carcinogen biotransformation by human-associated bacteria, the microbiota, has not yet been systematically investigated. We tested...

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Literature Corpus work
54a28473-eca5-5f4b-8be8-840e4e9a75ad
DOI
10.1101/2024.05.20.595058
Open publication

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Systematic analysis of gut bacterial carcinogen metabolism and its functional consequencesDOI 10.1101/2024.05.20.595058
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