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Article

Herpes simplex virus type 1 thymidine kinase gene expression in Escherichia coli.

Gene - 1 Jan 2000

Becker Y, Shtram Y, Honigman A, Laban A, Cohen A

Abstract excerpt

The HSV-1 thymidine kinase (TK) gene of Herpes simplex virus was inserted into plasmids pBR322, pMOB45 and pHA10. The recombinant hybrid plasmids were used to transfect a tdk- mutant of Escherichia coli (Ky895) and the synthesis of the viral TK in the bacterial host was studied. Recombinant plasmids containing the entire BamHI-BamHI DNA fragment carrying the viral TK gene and the upstream sequences containing its...

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PMID: 6301950
DOI: 10.1016/0378-1119(83)90146-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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