Article
Herpes simplex virus type 1 thymidine kinase gene expression in Escherichia coli.
Gene - 1 Jan 2000
Becker Y, Shtram Y, Honigman A, Laban A, Cohen A
Abstract excerpt
The HSV-1 thymidine kinase (TK) gene of Herpes simplex virus was inserted into plasmids pBR322, pMOB45 and pHA10. The recombinant hybrid plasmids were used to transfect a tdk- mutant of Escherichia coli (Ky895) and the synthesis of the viral TK in the bacterial host was studied. Recombinant plasm...
Topics
- DNA, Recombinant
- Escherichia coli
- Genes
- Genes, Viral
- Mutation
- Plasmids
- Simplexvirus
- Thymidine Kinase
