Article
Molecular cloning and expression of the bacteriophage T7 0.7(protein kinase) gene.
Virology - 1 Feb 1992
Michalewicz J, Nicholson A W
Abstract excerpt
The bacteriophage T7 0.7 gene encodes a protein which supports viral reproduction under specific suboptimal growth conditions. The 0.7 protein (gp0.7) shuts off host RNA polymerase-catalyzed transcription and also expresses a serine/threonine-specific, cAMP-independent protein kinase (PK) activity. To determine the role of the gp0.7 PK in viral reproduction, the 0.7 gene of the T7(JS78) mutant phage--whose gp0.7...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA, Viral
- Electrophoresis, Polyacrylamide Gel
- Gene Expression Regulation, Viral
- Glycoproteins
- Molecular Sequence Data
- Mutation
- Phosphorylation
- Phosphotransferases