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Article

Evaluation of the T-REx transcription switch for conditional expression and regulation of HSV-1 vectors.

Virus genes - 1 Feb 2008

Knopf Charles Werner, Zavidij Oksana, Rezuchova Ingeborg, Rajcáni Július

Abstract excerpt

Herpes simplex virus 1 (HSV-1) strain ANG and ANGpath were cloned as bacterial artificial chromosome (BAC). Two different types of BAC genomes were obtained. BAC genomes of type I contained the BAC replicon at the intended target region between the genes of UL48 and UL49. In BAC genomes of type II, the BAC sequences were found to be aberrantly fused between the termini of the HSV-1 genome. Both the BAC types were...

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PMID: 18193347
DOI: 10.1007/s11262-007-0178-9

Genes

ANG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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