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Article

Investigations in the transforming activity of temperature-sensitive mutants of herpes simplex virus.

Virologie - 1 Jan 2000

Danielescu G, Baba C, Cajal N, Anton D, Botnariuc I, Constantinescu O, Muţiu A

Abstract excerpt

Transformation of rat embryo fibroblast was induced by a temperature-sensitive mutant of herpes simplex virus type 2. Transformation was scored using the morphological criterion of focus formation and the cell changes that lead to the final focus are described. Virus genome persistence in the transformed cell line was demonstrated by the presence of virus-specific membrane antigens and by the specificity of...

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PMID: 6280377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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