Article
Herpes simplex virus type 2 and pseudorabies virus associated growth factors and their role in the latency in vitro.
Acta virologica - 1 Dec 1992
Golais F, Csabayová M, Lesko J, Bystrická M, Sabó A
Abstract excerpt
A putative herpes simplex virus type 2 (HSV-2) growth factor (HSGF-2) was detected in a crude extract from virus infected mouse embryo cells. This factor, similar to previously described pseudorabies virus (PRV) associated growth factor (PRGF) was shown to have ability to morphologically transform non-transformed cells and to repress the transformed phenotype of transformed cells. Both activities could be...
Topics
- Animals
- Antibodies, Monoclonal
- Antibodies, Viral
- Azacitidine
- Cell Transformation, Neoplastic
- Embryo, Mammalian
- Glycoproteins
- Growth Substances
- HeLa Cells
- Herpesvirus 1, Suid
- Humans