Article
High-resolution one-dimensional isoelectric focusing of mouse MHC class I antigens. Identification of natural and experimentally induced class I antigens.
Immunogenetics - 1 Jan 1990
Ljunggren H G, Oudshoorn-Snoek M, Masucci M G, Ploegh H L
Abstract excerpt
A method is described for a biochemical comparison of mouse class I antigens utilizing antisera with a monomorphic pattern of reaction and high-resolution one-dimensional isoelectric focusing (1D-IEF). The most commonly occurring and studied H-2K and D alleles were identified in a comparison of over 40 mouse strains. By comparing H-2 mutant mouse strains, cell lines transfected with defined class I genes, or mice...
Topics
- Alleles
- Animals
- Antigens, Surface
- H-2 Antigens
- Haplotypes
- Histocompatibility Antigens Class I
- Isoelectric Focusing
- Mice
- Mice, Transgenic
- Rabbits
- Transfection
