Frequency and spectrum of mutations across 94 cancer predisposition genes in African American women with invasive breast cancer.

Abstract excerpt

African American women are at increased risk of being diagnosed at a young age and/or with triple negative breast cancer, both factors which are included in current guidelines for identifying women who may benefit from genetic testing. Commercial breast cancer predisposition genetic panels, based largely on data derived from women of European ancestry, may not capture the full spectrum of cancer predisposition...

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