Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary ovarian cancer in women with African ancestry: a scoping review.

Familial cancer - 31 Jan 2026

Rossouw Bianca, Araujo Monica, Krause Amanda, Baine-Savanhu Fiona

Abstract excerpt

This scoping review explored genetic variants associated with hereditary ovarian cancer in women of African ancestry. Around 20% of ovarian cancers are hereditary, with BRCA1 and BRCA2 variants accounting for 20–55% of these cases, while other implicated genes include BRIP1, ATM, RAD51C, RAD51D, and the Lynch syndrome genes. The genetic basis of ovarian cancer in women of African ancestry, however, remains poorly...

Topics

Join the communities discussing this publication.

Black People
BRCA1 Protein
BRCA2 Protein
BRIP1 gene
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Testing

Germ-Line Mutation

Ovarian Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 41619087
DOI: 10.1007/s10689-026-00530-x
PMCID: PMC12860814

Genes

BRCA1
BRCA2
ATM
BRIP1
RAD51C
RAD51D

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary ovarian cancer in women with African ancestry: a scoping review.PMID 41619087Read ↗

BRCA1 and BRCA2 pathogenic sequence variants in women of African origin or ancestry.Semantic proximity Read ↗

Hereditary variants of unknown significance in African American women with breast cancer.Semantic proximity Read ↗

Cancer genetic mutation prevalence in sub-Saharan Africa: A review of existing data.Semantic proximity Read ↗

Beyond BRCA: Genetic testing for gynaecological cancers in South Africa.Semantic proximity Read ↗

Breast Cancer: Genetic Risk Assessment, Diagnostics, and Therapeutics in African Populations.Semantic proximity Read ↗

Frequency and spectrum of mutations across 94 cancer predisposition genes in African American women with invasive breast cancer.Semantic proximity Read ↗

Hereditary ovarian cancer: not only BRCA 1 and 2 genes.Semantic proximity Read ↗

Association of Breast and Ovarian Cancers With Predisposition Genes Identified by Large-Scale Sequencing.Semantic proximity Read ↗

Inherited predisposition to breast cancer among African American women.Semantic proximity Read ↗

Hereditary ovarian cancer: beyond the usual suspects.Semantic proximity Read ↗

Inherited Mutations in Women With Ovarian Carcinoma.Semantic proximity Read ↗

Frequency of mutations in a large series of clinically ascertained ovarian cancer cases tested on multi-gene panels compared to reference controls.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.