Article
BRCA1 and BRCA2 mutations across race and ethnicity: distribution and clinical implications.
Current opinion in obstetrics & gynecology - 1 Feb 2010
Kurian Allison W
Abstract excerpt
PURPOSE OF REVIEW: To summarize evidence on the prevalence and spectrum of BRCA1 and BRCA2 BRCA1/2 mutations across racial and ethnic groups and discuss implications for clinical practice. RECENT FINDINGS: The prevalence of BRCA1/2 mutations is comparable among breast cancer patients of African, Asian, white, and Hispanic descent: approximately 1-4% per gene. Among ovarian cancer patients in North America,...
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