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Article

Genomic structural equation modeling reveals novel genetic loci and pathways in panvascular disease.

Medicine - 21 Aug 2026

Gao Lulu, Jin Baihan, Mei Kun, Zhang Xiaoying

Abstract excerpt

The genetic architecture underlying panvascular disease-related traits remains poorly understood. By leveraging genomic structural equation modeling (Genomic SEM) and a variety of post-GWAS methods, we estimated causal single-nucleotide polymorphisms (SNPs) that are independent of panvascular disease variants and identified a total of 2799 genome-wide significant loci. We applied multiple transcriptome-wide...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42629728
DOI: 10.1097/MD.0000000000050194
PMCID: PMC13502809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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