Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genetic basis of peripheral arterial disease: current knowledge, challenges, and future directions.

Circulation research - 24 Apr 2015

Kullo Iftikhar J, Leeper Nicholas J

Abstract excerpt

Several risk factors for atherosclerotic peripheral arterial disease (PAD), such as dyslipidemia, diabetes mellitus, and hypertension, are heritable. However, predisposition to PAD may be influenced by genetic variants acting independently of these risk factors. Identification of such genetic variants will provide insights into underlying pathophysiologic mechanisms and facilitate the development of novel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenesis, Genetic
Share to Forecasting
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Genome-Wide Association Study

Share to High-Throughput Nucleotide Sequencing

Share to Peripheral Arterial Disease

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 25908728
DOI: 10.1161/CIRCRESAHA.116.303518
PMCID: PMC4410432

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetic basis of peripheral arterial disease: current knowledge, challenges, and future directions.PMID 25908728Read ↗

Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology.Semantic proximity Read ↗

Peripheral Arterial Disease Genetics: Progress to Date and Challenges Ahead.Semantic proximity Read ↗

Biomarkers and Genetics in Peripheral Artery DiseaseSemantic proximity Read ↗

[Advances in research on the genetics of peripheral arterial disease].Semantic proximity Read ↗

Peripheral artery disease and genetics: is there a cause-and-effect relationship?Semantic proximity Read ↗

Genetic association studies in peripheral arterial disease.Semantic proximity Read ↗

The Genetic Architecture of the Etiology of Lower Extremity Peripheral Artery Disease: Current Knowledge and Future Challenges in the Era of Genomic Medicine.Semantic proximity Read ↗

The Role of Genetics in Managing Peripheral Arterial Disease.Semantic proximity Read ↗

Genome-Wide Association Study of Peripheral Artery Disease.Semantic proximity Read ↗

Lipid-associated GWAS loci as important markers of the risk, severity, and clinical course of peripheral artery disease.Semantic proximity Read ↗

Peripheral arterial disease in diabetes: is there a role for genetics?Semantic proximity Read ↗

Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: a scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.