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Article

Chromosome Y Regulates Survival Following Murine Coxsackievirus B3 Infection

1 Jan 2012

Abstract excerpt

Coxsackievirus B3 (CVB3) contributes to the development of myocarditis, an inflammatory heart disease that predominates in males, and infection is a cause of unexpected death in young individuals. Although gonadal hormones contribute significantly to sex differences, sex chromosomes may also influence disease. Increasing evidence indicates that Chromosome Y (ChrY) genetic variants can impact biological functions...

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PMID: 22384388
DOI: 10.1534/g3.111.001610

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