Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic-proteomic network crosstalk at birth across HLA risk groups in type 1 diabetes.

Frontiers in immunology - 1 Jan 2026

Alipoor Shamila D, Ahrens Angelica, Åkesson Julia, Ludvigsson Johnny

Abstract excerpt

Introduction: Type 1 diabetes (T1D) arises from genetic predisposition, where early-life biological events may contribute to later disease development. Using the population-based ABIS (All Babies in Southeast Sweden) birth cohort, we recently reported that cord blood DNA methylation signatures differ between individuals carrying high- and low-risk HLA genotypes who later develop T1D, suggesting that distinct...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fetal Blood

Share to HLA Antigens

Share to Infant, Newborn

Share to Protein Interaction Maps

Share to Proteomics

Source

Open in PubMed Open full text

Identifiers

PMID: 42592180
DOI: 10.3389/fimmu.2026.1836758
PMCID: PMC13464127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic-proteomic network crosstalk at birth across HLA risk groups in type 1 diabetes.PMID 42592180Read ↗

Epigenetic analyses suggest different pathways during pregnancy for development of type 1 diabetes in children with high versus low-neutral human leukocyte antigen-risk.Semantic proximity Read ↗

Genetics of circulating proteins in newborn babies at high risk of type 1 diabetesSemantic proximity Read ↗

Allele-specific methylation of type 1 diabetes susceptibility genes.Semantic proximity Read ↗

Genetic and epigenetic factors in etiology of diabetes mellitus type 1.Semantic proximity Read ↗

Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes.Semantic proximity Read ↗

The type 1 diabetes - HLA susceptibility interactome--identification of HLA genotype-specific disease genes for type 1 diabetes.Semantic proximity Read ↗

Early DNA methylation changes in children developing beta cell autoimmunity at a young ageSemantic proximity Read ↗

Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes.Semantic proximity Read ↗

Epigenetic And Transcriptomic Alterations in Offspring Born To Women With Type 1 Diabetes (The EPICOM Study)Semantic proximity Read ↗

Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes.Semantic proximity Read ↗

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes.Semantic proximity Read ↗

Longitudinal DNA methylation differences precede type 1 diabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.