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Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes

22 Apr 2025

Abstract excerpt

Type 1 diabetes is a chronic, autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreas. Early detection can facilitate timely intervention, potentially delaying or preventing disease onset. Circulating proteins reflect dysregulated biological processes and offer insights into early disease mechanisms. Here, we construct a genome-wide pQTL map of 1985 proteins in 695 newborn...

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PMID: 40263317
DOI: 10.1038/s41467-025-58972-3

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