Predictive models of the genetic bases underlying budding yeast fitness in multiple environments.

Abstract excerpt

The ability of organisms to adapt and survive depends on the effects of genes and the environment on fitness. However, the multigenic nature of fitness and genotype-by-environment interactions hinder our understanding of the genetic basis of fitness. Here, we established fitness prediction models for 35 environments using machine learning and existing fitness data and different genetic variant types for...

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• Benomyl
• DNA Copy Number Variations
• Environment
• Gene-Environment Interaction
• Genetic Fitness