Evolutionary adaptation proceeds through a small number of phenotypic modules.

doi:10.1093/molbev/msag183

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Article

Evolutionary adaptation proceeds through a small number of phenotypic modules.

Molecular biology and evolution - 1 Aug 2026

Donyavi Mohammad Hossein, Ghelich Reza, Schmidlin Kara, Kinsler Grant, Geiler-Samerotte Kerry

Abstract excerpt

Understanding how the myriad molecular impacts of mutation percolate to influence higher-order traits and ultimately fitness requires compressing a many-to-many mapping into something tractable. Decades of theoretical work suggest this may be possible because biological systems are modular: effec...

Topics

Phenotype
Genetic Fitness
Selection, Genetic
Mutation
Biological Evolution
Saccharomyces cerevisiae
Adaptation, Biological
Evolution, Molecular
Adaptation, Physiological
Genetic Pleiotropy

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