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Genetic Variations in TNFAIP3 and CTLA4 and Their Association with Circulating TNF-α and sCTLA4 Levels in Kurdish Patients with Rheumatoid Arthritis.

Genes - 18 Jul 2026

Ishaq Sonia Elia, Rasheed Taban Kamal, Albarzinji Niaz, Smail Shukur Wasman

Abstract excerpt

Background/Objectives: Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by sustained synovial inflammation and systemic immune activation. Genetic polymorphisms in key immune-regulatory pathways are thought to influence both disease susceptibility and progression. This study aimed to characterize sequence variation within selected coding regions of TNFAIP3 and CTLA4 in Kurdish patients with RA and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to CTLA-4 Antigen

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Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 42510861
DOI: 10.3390/genes17070821
PMCID: PMC13409714

Genes

CTLA4
TNFAIP3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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