Article
Single nucleotide polymorphisms in TNFAIP3 were associated with the risks of rheumatoid arthritis in northern Chinese Han population.
BMC medical genetics - 15 May 2014
Zhang Xingang, Li Wei, Zhang Xinpeng, Zhao Liang, Zhang Xiaoli, Jiang Li, Guo Yun, Zhang Jin, Liang Zaifu, Wang Xiaofei
Abstract excerpt
BACKGROUND: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic destructive inflammation in synovial joints. It is well known that genetic and environmental risk factors and their interaction contribute to RA pathogenesis. This study aimed to investigate the association between the critical polymorphisms in the tumor necrosis factor α (TNFα)-induced protein 3(TNFAIP3) gene and the...
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