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Article

A sequencing study of CTLA4 in Pakistani rheumatoid arthritis cases.

PloS one - 1 Jan 2020

Aslam Muhammad Muaaz, Jalil Fazal, John Peter, Fan Kang-Hsien, Bhatti Attya, Feingold Eleanor, Demirci F Yesim, Kamboh M Ilyas

Abstract excerpt

Rheumatoid arthritis (RA) is a multifactorial autoimmune disease. The interaction of genetic and environmental factors is likely necessary for RA. Among potential genetic factors, many major histocompatibility complex (MHC) and non-MHC variants may be involved in RA susceptibility. CTLA4 is involved in the regulation of T-cell response during an immune reaction, and multiple CTLA4 single nucleotide polymorphisms...

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Share to CTLA-4 Antigen
Share to Genotype
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 32946523
DOI: 10.1371/journal.pone.0239426
PMCID: PMC7500603

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