Article
Interaction of a genetic sum score of risk alleles associated with coronary artery disease by physical activity in the Heinz Nixdorf Recall study.
BMC cardiovascular disorders - 25 Jul 2026
Penther Johannes, Wilkening Nicola, Mavarani Laven, Erbel Raimund, Schmidt Börge
Abstract excerpt
OBJECTIVES: This study aimed to investigate the interaction between a genetic risk score for coronary artery disease (CAD) and measures of physical activity on coronary artery calcification (CAC) in a population-based cohort. Specifically, it sought to determine whether physical exercise, known to be protective against high CAC, influences the expression of genetic risk factors for CAD. METHODS: Data were...
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