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Physical activity, genetic predisposition, and incident cardiovascular disease: Prospective analyses of the UK Biobank

10 May 2025

Abstract excerpt

BACKGROUND: It is unclear whether physical activity can benefit participants with high genetic predisposition to cardiovascular disease. We examined the joint associations of intensity-specific physical activity and genetic predisposition (based on polygenetic risk score) with incident coronary heart disease (CHD), stroke, and atrial fibrillation (AF). METHODS: This prospective cohort study included 303,950...

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Genetic Associations and Epidemiology
Genetics and Physical Performance

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40355085
DOI: 10.1016/j.jshs.2025.101055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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